My example is this simple landscape with a house in the distance.
Firstly, the house shows up because it is set against a dark background...
remember: Light against Dark and Dark against Light always has impact.
But moving on to the point of this post...
Never place the main subject in the Middle of a painting
Always put it slightly off centre, it's far more interesting to the viewer -
Work with the One-third Rule
If I flip this painting you will see that you could have the point of interest on the right
and it works just as easily because it is in the one-third section of the painting.